Plasmid Purification Market Is Estimated High Growth Owing To Growing Pharmaceutical And Biotechnology Industries
- Ronak Shah
- U.S.A
- January 14, 2025

The plasmid purification market is estimated to be valued at US$ 1.98 Bn in 2024 and is expected to exhibit a CAGR of 11.4% over the forecast period 2024- 2031, as highlighted in a new report published by Coherent Market Insights’The growth of the plasmid purification market is majorly driven by the increasing demand for plasmid DNA in pharmaceutical and biotechnology industries.
Plasmid DNA finds wide applications in gene therapy, DNA vaccinations, monoclonal antibody production, and stem cell research. Moreover, advancements in genome engineering techniques such as CRISPR are augmenting the demand for high-quality and high-yield plasmid DNA. The requirement of plasmid DNA for various applications is further projected to propel market growth over the forecast period.
Key Market Trends: Kits Segment To Witness Lucrative Growth-The kits segment dominated the market in 2022, in terms of revenue. Kits provide convenience, reproducibility, and standardized plasmid purification. They help avoid complex manual plasmid purification procedures and are less prone to human errors. Thus, kits offer advantages such as cost-saving over time, consistency in performance, and ease-of-use. This is expected to increase the preference for kits among researchers as well as industry players over the forecast period.
Gene Therapy Emerges As A Key Application-Gene therapy has emerged as a promising therapeutic approach for several medical conditions including cancer, genetic disorders, and infectious diseases. Plasmid DNA plays a vital role as a gene delivery vector in gene therapy approaches. The commercialization of advanced gene therapies and robust pipeline of gene therapy candidates in clinical trials are expected to propel the demand for high-quality and high-yield plasmid DNA. This, in turn, is projected to contribute to the growth of the global plasmid purification market during the forecast period.
Plasmid Purification Market Opportunity By Product And Service Type Insights-The plasmid purification market based on product and service type is segmented into kits, reagents and consumables, and plasmid purification services. In 2019, the kits segment accounted for the highest market share of around 60%. Plasmid purification kits offer a standardized and streamlined process for plasmid isolation and purification. They are convenient and easy-to-use as they contain all the necessary buffers, columns and other components required for plasmid purification. The availability of a wide range of plasmid purification kits catering to different DNA quantities and plasmid sizes is driving the growth of this segment.
By Grade Insights-Based on grade, the plasmid purification market is divided into research grade and GMP/clinical grade. The research grade segment holds the highest share owing to increasing R&D investment in drug discovery and development. Research-grade plasmids are suitable for lab-based experiments and research purposes. However, the GMP/clinical grade segment is expected to witness faster growth during the forecast period as it is essential for further studies involving humans and clinical trials. Proper manufacturing and quality control of GMP/clinical grade plasmids is important to avoid contaminants and ensure safety for clinical applications.
Key Market Takeaways
The global plasmid purification market size was valued at USD 1.98 billion in 2024 and is anticipated to witness a CAGR of 11.4% during the forecast period. Growth is attributed to increasing recombinant DNA technology adoption and rising demand for plasmid purification kits and services in biotech and pharmaceutical industry for gene therapies and vaccine development.
On the basis of product and service type, the kits segment is expected to hold a dominant position owing to its standardization, affordability and easy-to-use nature.
Based on grade, the research grade segment held the highest share in 2019. However, the GMP/clinical grade segment is anticipated to witness faster growth due to growing clinical research activities.
By region, North America is expected to dominate the global plasmid purification market over the forecast period due to major biotech and pharma companies domiciled in the region and increasing R&D spending.
Competitor Insights:Some of the prominent players operating in the plasmid purification market include illumina Inc., MCLAB, QIAGEN, HiMedia Laboratories, Thermo Fisher Scientific, and New England Biolabs among others. These players are focusing on new product launches and expansion strategies to strengthen their market position.
Recent Developments: In mid-August, Omega Bio-tek, a leading life sciences tools company, launched two new plasmid miniprep kits – the Mag-Bind Plasmid MiniPrep Kit and QuickLyse Miniprep Kit. Both kits are designed for rapid purification of high-quality plasmid DNA from bacterial cultures on a mini scale. The new kits offer significant improvements over existing miniprep technologies, including faster processing times, higher yields, and superior DNA quality free of contaminants. They also have a simplified workflow requiring minimal hands-on time. Omega officially released the kits at the genomics summit held in San Diego in August. More information in full report.